Technology that changes everything

Engineered with your practice and your patients in mind, the Auryon System is designed with industry-leading technology and features that allow you to treat any lesion you encounter, all with a single device built to streamline how you handle PAD.1-3

The Auryon System for peripheral atherectomy in PAD treatment

Welcome to what’s next

With the Auryon System, you get to harness the next generation of peripheral atherectomy technology.

An icon of two triangles with a blue dot in the middle with a line connecting another blue dot on the outside


Treats all levels of calcification1-3

  • Indicated for in-stent restenosis*
  • Treats infrainguinal lesions both above and below the knee (including below the ankle)
  • Built-in off-centering mechanism for eccentric lesions in largest catheter

*Only the 2.0- and 2.35-mm catheters are indicated for ISR.

Circle icon with three blue dots in the middle with curved lines connecting the dots to the top and bottom of the circle


Protective of the vessel wall3-5

  • Performs targeted biological reactions to address risk of perforations
  • Nonreactive to contrast media for simultaneous ablation and observation of fluoroscopy image
  • Includes built-in aspiration to address risk of embolization

Built-in aspiration available only with the 2.0- and 2.35-mm catheters.

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Designed for your lab1-3,6

  • Designed to be portable, uses a 110V outlet, has a touch screen, and emits low acoustic noise
  • Has the potential to debulk in fewer passages
  • Small footprint, easy installation and storage

Intuitive touch-screen controls

LED activity status indicator

Solid-state laser contains no gas and requires no calibration

Foot pedal for hands-free activation

Aspiration available with 2 catheters

The front of the Auryon System for peripheral atherectomy in PAD treatment

Ergonomic maneuverability

Small footprint in your office space

Standard 110V wall plug

Foot pedal and power cord storage

The back of the Auryon System for peripheral atherectomy in PAD treatment

  • Below the knee/ankle
  • Reference vessel diameter: ≥1.4 mm2

  • Below the knee
  • Reference vessel diameter: ≥2.25 mm2

  • Reference vessel diameter: ≥3.0 mm2
  • Built-in aspiration capability
  • Cleared for ISR

  • Reference vessel diameter: ≥3.6 mm2
  • Built-in aspiration capability
  • Off-centering mechanism
  • Cleared for ISR

The Auryon System catheters for peripheral atherectomy in PAD treatment

Advanced efficiency3

Auryon Logo


198 lb


29 in


37 in


13.3 in


355 nm class IV laser system

Power type

110V wall outlet

Small footprint, lightweight portability, and convenient storage for your office.
PHILIPS CVX-300 logo


650 lb


49 in


41.9 in


24 in


308 nm class IV laser system

Power type

208-230 VAC single phase power US wall outlet receptacle NEMA L6-30R, Hubble Part # HBL2620, 250BAC, 30A wall mount twist lock7

Treat any infrainguinal artery1,3

Purpose-built catheters are designed to treat both above and below the knee, including the ankle.

Transparent left leg illustration showing infrainguinal vasculature
Popliteal + superficial
femoral artery

2.35-mm catheter

  • Reference vessel diameter: ≥3.6 mm2
  • Built-in aspiration capability
  • Off-centering mechanism
  • Cleared for ISR
  • French size 7 Fr
The Auryon System 2.35-mm catheter
Femoropopliteal +
tibioperoneal trunk

2.0-mm catheter

  • Reference vessel diameter: ≥3.0 mm2
  • Built-in aspiration capability
  • Cleared for ISR
  • French size 6 Fr
The Auryon System 2.0-mm catheter
Tibial + femoropopliteal

1.5-mm catheter

  • Below the knee
  • Reference vessel diameter: ≥2.25 mm2
  • French size 5 Fr
  • Now available in 225cm XL length
The Auryon System 1.5-mm catheter
Below the ankle + tibials

0.9-mm catheter

  • Reference vessel diameter: ≥1.4 mm2
  • French size 4 Fr
  • Now available in 225cm XL length
The Auryon System 0.9-mm catheter

All catheters work over a standard 0.014-inch guide-wire.

The science

Powerful. And precise.

The Auryon System is designed to deliver an optimized wavelength, pulse width, and amplitude to remove calcified lesions while preserving vessel wall endothelium.3,4,8

Wavelength, pulse width, and amplitude image
Wavelength (nm)
The distance between 2 successive waves determines absorption rate and penetration depth
Pulse width (ns)
The duration of each pulse determines levels of diffusion
Amplitude (mJ/mm2)
The height of the wave determines power
Wavelength icon

Why wavelength matters9-12

  • Each type of tissue interacts differently with a given wavelength
  • To initiate a photochemical effect, the photon energy of the beam must be higher than the dissociation energy of the target molecular bond
  • Longer wavelengths are absorbed at shallower depths than shorter wavelengths, resulting in lower photon energies
The Auryon System produces a photon energy of 3.5 eV, which is low enough to be nonreactive to vessel endothelium, but high enough to vaporize calcium.4,8
Pulse icon

Why pulse width and amplitude matter9,11,13,14

  • To localize the effects to the target tissue without thermal damage, the energy delivered needs to be faster than the time it takes for the heat to diffuse
  • As the type of plaque progresses from visible intimal thickening to hard, the amplitude (power) needed to ablate increases
  • Greater amplitude is achieved with shorter pulses, which can deposit energy before thermal diffusion occurs
The Auryon System has a pulse width of 10 to 25 ns, ensuring enough power to target the lesion and spare the vessel.3

How the Auryon System combines power and precision

The precision of 355-nm wavelength4,5

  • 3x higher affinity for lesion tissue vs vessel endothelium, giving you the ability to ablate the lesion while preserving vessel endothelium
  • Nonreactive to contrast media, allowing you to simultaneously debulk lesions and monitor fluoroscopy images

Power to debulk any type of lesion (from thrombotic to severely calcified)3,8

  • 10- to 25-ns pulse width with 40-Hz amplitude allows for high power output, resulting in calcium debulking
  • Plasma formation results in vaporization of lesion tissue without thermal ablation

Efficient ablation

A shorter pulse is efficient at material removal by delivering more of the total energy above the biological threshold.14

Blue circle with arrows pointing out showing an expandable graph
Blue circle with arrows pointing in showing a minimized graph

Efficient ablation graph

Efficient ablation graph

See how the Auryon System performed in a multinational trial with 97 patients.1-3

Trial data
References: 1. Rundback J, Chandra P, Brodmann M, Weinstock B, Sedillo G, Cawich I, et al. Novel laser-based catheter for peripheral atherectomy: 6-month results from the Eximo Medical B-Laser™ IDE study. Catheter Cardiovasc Interv. 2019;1-8. 2. Shammas NW, Chandra P, Brodmann M, Weinstock B, Sedillo G, Cawich I, et al. Acute and 30-day safety and effectiveness evaluation of Eximo Medical’s B-Laser™, a novel atherectomy device, in subjects affected with infrainguinal peripheral arterial disease: Results of the EX-PAD-03 trial. Cardiovas Revasc Med. 2020;21(1):86-92. 3. Auryon. Instructions for use. AngioDynamics; 2019. 4. Herzog A, Bogdan S, Glikson M, Ishaaya AA, Love C. Selective tissue ablation using laser radiation at 355 nm in lead extraction by a hybrid catheter; a preliminary report. Lasers Surg Med. 2016;48(3):281-287. 5. Herzog A, Steinberg I, Gaisenberg E, Nomberg R, Ishaaya AA. A route to laser angioplasty in the presence of fluoroscopy contrast media, using a nanosecond-pulsed 355-nm laser. IEEE J Sel Top Quantum Electron. 2016;22(3):342-347. 6. Kuczmik W, Kruszyna L, Stanisic MG, Dzieciuchowicz L, Ziaja K, Zelawski W, et al. Laser atherectomy using the novel B-Laser™ catheter, for the treatment of femoropopliteal lesions: twelve-month results from the EX-PAD-01 study. Not yet published. 7. Spectranetics Corporation. CVX-300 Excimer Laser System: Operator’s Manual. Version 28. 2019:1-56. 8. Vogel A, Venugopalan V. Mechanisms of pulsed laser ablation of biological tissues. Chem Rev. 2003;103(2):577-644. 9. Akkus NI, Abdulbaki A, Jimenez E, Tandon N. Atherectomy devices: technology update. Med Devices (Auckl). 2015;8:1-10. 10. Rawlins J, Din JN, Talwar S, O’Kane P. Coronary intervention with the Excimer laser: review of the technology and outcome data. Interv Cardiol. 2016;11(1):27-32. 11. Jacques SL. Role of tissue optics and pulse duration on tissue effects during high-power laser irradiation. Appl Opt. 1993;32(13):2447-2454. 12. Beek JF, van der Meulen FW, Gijsbers GHM, Welch AJ, Hogervorst W, van Gemert MJC. Laser physics and laser-tissue interaction. Laser Surg Child. 1998;10-49. 13. Taylor RS, Higginson LAJ, Leopold KE. Dependence of the XeCl laser cut rate of plaque on the degree of calcification, laser fluence, and optical pulse duration. Lasers Surg Med. 1990;10(5):414-419. 14. Photonics Media. Shorter pulse widths improve micromachining. Published June 2013. Accessed March 20, 2020.